Dr. William Stubbeman

Dr. William Stubbeman is a trailblazer in the realm of psychiatric treatment, specializing in Transcranial Magnetic Stimulation (TMS). With a rich background in mechanical and aerospace engineering from Princeton University, and medical training from Columbia University, Dr. Stubbeman's approach to mental health is profoundly influenced by a robust foundation in both engineering and medicine. His transition from an Ear, Nose, and Throat surgeon at UCLA to a psychiatrist was driven by his fascination with the brain's complexities and its impact on human behavior.

Certified in TMS, Dr. Stubbeman trained under luminaries such as Dr. Sarah H. Lisanby at Duke and Dr. Alvaro Pascual-Leone at Harvard, learning at the forefront of neuromodulation technologies. His innovative TMS protocol, which has been featured in the July 2018 issue of the Brain Stimulation Journal, achieves remarkably high remission rates in patients with major depressive disorder—particularly those who have not responded to traditional treatments.

After completing a two-year research fellowship at UCLA, where he published extensively on the prediction of antidepressant and ECT response, Dr. Stubbeman established a successful private psychiatry practice in West Los Angeles. Here, he specializes in treatment-refractory psychopharmacology and has expanded his practice to include advanced TMS treatments. His work is characterized by a dedication to reducing the dependency on medications by employing precision-targeted treatment strategies that offer new hope to those grappling with severe depression.

Dr. Stubbeman’s Research:
Bilateral neuronavigated 20Hz theta burst TMS for treatment refractory depression: An open label study
William F. Stubbeman, Bijan Zarrabi, Silvia Bastea, Victoria Ragland, Raya Khairkhah (2018). Bilateral Neuronavigated TBS-20Hz TMS brought more than two-thirds of treatment refractory depressed patients to remission. TBS-20Hz may be critical for obtaining higher remission rates. Controlled trials are warranted. Brain Stimulation Journal, online.
Changes in prefrontal activity characterize clinical response in SSRI nonresponders: a pilot study
Cook, I. A., Leuchter, A. F., Morgan, M. L., Stubbeman, W., Siegman, B., & Abrams, M. (2005). Changes in prefrontal activity characterize clinical response in SSRI nonresponders: a pilot study. Journal of psychiatric research, 39(5), 461-466.
Pretreatment neurophysiologic function and ECT response in depression
Stubbeman, W. F., Leuchter, A. F., Cook, I. A., Shurman, B. D., Morgan, M., Gunay, I., & Gonzalez, S. (2004). Pretreatment neurophysiologic function and ECT response in depression. The journal of ECT, 20(3), 142-144.
Early changes in prefrontal activity characterize clinical responders to antidepressants
Cook, I. A., Leuchter, A. F., Morgan, M., Witte, E., Stubbeman, W. F., Abrams, M., … & Uijtdehaage, S. H. (2002). Early changes in prefrontal activity characterize clinical responders to antidepressants. Neuropsychopharmacology, 27(1), 120-131.
Corrigendum to ‘Neurophysiologic predictors of treatment response to fluoxetine in major depression’
Cook, I. A., Leuchter, A. F., Witte, E., Abrams, M., Uijtdehaage, S. H., Stubbeman, W., … & Dunkin, J. J. (2000). Corrigendum to ‘Neurophysiologic predictors of treatment response to fluoxetine in major depression’:[Psychiatry Research 85 (1999) 263–273] 1PII of original article: S0165-1781 (99) 00010-41. Psychiatry Research, 95(1), 87.
Neurophysiologic predictors of treatment response to fluoxetine in major depression
Cook, I. A., Leuchter, A. F., Witte, E., Abrams, M., Uijtdehaage, S. H., Stubbeman, W., … & Anderson-Hanley, C. (1999). Neurophysiologic predictors of treatment response to fluoxetine in major depression. Psychiatry research, 85(3), 263-273.
Electromechanical analogs of human reflexes
Littman, M. G., Liker, M., Stubbeman, W., Russakow, J., McGEE, C., Gelfand, J., & Call, B. J. (1989). Electromechanical Analogs of Human Reflexesa. Annals of the New York Academy of Sciences, 563(1), 184-193.